2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. CRAC Channel
  5. CRAC Channel Activator

CRAC Channel Activator

CRAC Channel Activator (1):

Cat. No. Product Name Effect Purity
  • HY-W009724
    2-Aminoethyl diphenylborinate
    		Activator 99.86%
    2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue.